Test your science knowledge
About one in eight men will develop prostate cancer during their lifetime. Most cases are manageable. But sometimes, the tumors can become aggressive and resist all known therapies. New strategies are needed to treat and prevent these forms of prostate cancer. Scientists at the Â鶹´«Ã½Ó³» (CSHL) Cancer Center are on the case. Take this quiz to find out more about CSHL’s cutting-edge breakthroughs in prostate cancer research.
Which of these vitamins, found in carrots and other leafy greens, has been shown to slow prostate cancer growth in mice?
CSHL Professor Lloyd Trotman and his team discovered that a Vitamin K supplement called menadione slows prostate cancer in mice. Their research sets the stage for potential pilot studies in human patients that may lead to new and effective prostate cancer therapies.
What is the term used to describe when cancer spreads from one organ, like the prostate, to other parts of the body?
CSHL Professor Adam Siepel and collaborators at Weill Cornell Medicine have developed a way to map cancer metastasis using DNA barcoding. Their roadmaps reveal that, in prostate cancer, a small number of aggressive cells make way for metastasis to the bones, liver, lungs, and lymph nodes.
True or false: Prostate cancer is the most common cancer among men in the United States?
Prostate cancer is the second-most common cancer affecting men after skin cancer. Early detection is crucial. CSHL Professor Michael Wigler, Research Professor Alexander Krasnitz, and colleagues developed a technique that could help determine whether a patient’s prostate tumor poses a lethal threat before they undergo surgery.
The RapidCaP mouse model for metastatic prostate cancer has been used to make which of these discoveries?
The Trotman lab developed RapidCaP in 2014. Since then, it has become an essential tool in prostate cancer research. The model has helped researchers uncover potential drug targets for prostate cancer, and develop new ways to predict whether tumors will become aggressive.
Prostate cancer can spread to other parts of the body by hijacking which of the following?
Prostate cancer has a lot of nerve(s). Like breast cancer and other forms of the disease, it can hijack nearby nerves to spread throughout the body. CSHL’s Jeremy Borniger is one of the first researchers to conduct in-depth studies of the connections between tumors and the nervous system. His pioneering work helped lay the foundation for the growing field of cancer neuroscience.
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